Sex Differences in Subjective Cognitive Decline: Findings from BRFSS (2015–2018)

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Title: Sex Differences in Subjective Cognitive Decline: Findings from BRFSS (2015–2018)
Presenter: Karen Schliep, PhD, MSPH; University of Utah, Department of Family and Preventive Medicine
Contributors: Lily Gu, University of Utah; Fares Qeadan, PhD, University of Utah
Date: 5/14/20
Brief Description: Studying potential risk factors of subjective cognitive decline with a focus on sex differences
Keywords/Main Subjects: Subjective cognitive decline (SCD), sex differences, dementia
Copyright: copyright Karen Schliep ©2020
Contact: karen.schliep@hsc.utah.edu

Abstract

Objective:

Prior research has indicated that at least 35% of dementia risk is amenable to prevention, but whether risk differs between men and women has not been fully explored. Our objective was to estimate the population attributable fraction (PAF) of potentially modifiable risk factors for subjective cognitive decline (SCD), with a focus on sex differences.

Methods:

Data were from respondents (45 years and older) who completed the BRFSS Cognitive Decline Module (2015–2018). SCD was assessed as answering yes to “experiencing confusion or memory loss that is happening more often or is getting worse in the last 12 months”. We calculated PAFs, stratified by sex, of nine known modifiable risk factors, accounting for the complex survey design.

Results:

The final study sample (N=216,838) included slightly more females (F) (53.7%) than males (M) (46.3%), but with similar reporting for SCD: F: 10.6%; M: 10.9%. Women, however, had lower overall PAF to explain SCD (49%) compared to men (55%), with slight differences in the PAFs for individual risk factors: limited education (F: 0.9%; M: 1.3%), deafness (F: 3.9%; M: 6.9%), social isolation (F: 2.3%; M: 3.7%); depression (F: 15.1%; M: 13.9%); smoking (F: 3.9%; M: 3.6%); physical inactivity (F: 7.1%; M: 7.7%); obesity (F: 4.0%; M: 2.1%); hypertension (F: 7.9%; M: 11.2%); and diabetes (F: 3.8%; M: 4.4%).

Conclusion:

We found nearly 50% of SCD may be amenable to prevention. Prevalence of SCD is similar between men and women, but there are slight differences in risk factors, notably deafness, obesity, and hypertension.

New Thinking on Sex, Gender, Transgender and Non-Binary Identities

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Title: New Thinking on Sex, Gender, Transgender and Non-Binary Identities
Presenter: Lisa Diamond, PhD, University of Utah
Date: 5/14/20
Brief Description: Expanding definitions of sex and gender and their role in women’s health
Keywords/Main Subjects: Gender, transgender healthcare, non-binary gender, marginalized genders, women’s health
Copyright: copyright Lisa Diamond ©2020
Contact: lisa.diamond@psych.utah.edu

Q&A Session

  1. How might a gender-neutral environment (free of pink and blue and girl vs boy-specific) affect behavioral development and adult outcomes on personality (e.g. shy vs assertive)?

One thing we know is that even if parents try to do that, there is NO way to prevent a child from experiencing that sort of gender-neutral environment unless you kept the child from leaving the house, reading children’s books, seeing movies or TV, etc. There are parents who have tried it, but the impact of the larger world ALWAYS intrudes.  So we don’t really know how it would affect a child if you could consistently create a less polarized environment.

  1. Is Utah one of the states proposing to ban gender affirming treatment in some form?

Utah is currently NOT one of the states proposing to ban gender affirmative therapy for youth.

  1. How can “women’s health clinics” better serve gender-diverse individuals, while continuing to provide a welcoming environment to cis women who are still ignorant to gender diversity?

I think a lot of it is messaging specifically to gender-diverse individuals. So, a clinic could continue to call itself a women’s health clinic, but could make sure to include information on, for example, flyers and websites clarifying that they treat ALL women who have EVER identified as women, including trans women and trans men.

The Role of Gender in the Diagnosis and Treatment of Complex Disorders

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Title: The Role of Gender in the Diagnosis and Treatment of Complex Disorders
Presenter: Laura Pace, MD, PhD, University of Utah
Date: 5/14/20
Brief Description: Discussing high levels of gender bias in care for complex, rare disorders that are more common in women
Keywords/Main Subjects: Ehlers-Danlos syndrome, dysautonomia, MCAS, immune disorders, gender bias, psychological injury
Copyright: copyright Laura Pace ©2020
Contact: MISSING

Modeling Protection through Preeclampsia

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Title: Modeling Protection through Preeclampsia
Presenter: Leah Owen, MD, PhD, University of Utah
Date: 5/14/20
Brief Description: Role of preeclampsia (materal physiology and pathology) in protecting against retinopathy of prematurity (ROP)
Keywords/Main Subjects: preeclampsia, ROP, BIRCWH
Copyright: copyright Leah Owen ©2020
Contact: leah.owen@hsc.utah.edu

Progesterone, Post-partum Women and Preventing Methamphetamine Use: Applying Maternal-Fetal Medicine’s Favorite Medicine to Perinatal Substance Abuse

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Title: Progesterone, Post-partum Women and Preventing Methamphetamine Use: Applying Maternal-Fetal Medicine’s Favorite Medicine to Perinatal Substance Abuse
Presenter: Marcela Smid, MD, MA, MS, University of Utah
Date: 5/14/20
Brief Description: A proposal to study effects of progesterone on preventing return to methamphetamine use in post-partum women
Keywords/Main Subjects: Post-partum, perinatal substance abuse, methamphetamine use, progesterone, prevention, maternal-fetal medicine
Copyright: copyright Marcela Smid ©2020
Contact: marcela.smid@hsc.utah.edu

Exploring Genetic Variation in Normal and Diseased Human Placentas

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Title: Exploring Genetic Variation in Normal and Diseased Human Placentas
Presenter: Nathan Blue, MD, University of Utah
Date: 5/14/20
Brief Description: Influences of genetic variation on placental insufficiency
Keywords/Main Subjects: Placental disease, placental insufficiency, stillbirth, genetic variation
Copyright: copyright Nathan Blue ©2020
Contact: nathan.blue@hsc.utah.edu

Content Warning:

  • Stillborn baby shown from 2:56 – 3:26

The Status of Women in Utah: Education, Leadership, and Well-Being

Title: The Status of Women in Utah: Education, Leadership, and Well-Being
Presenter: Susan Madsen, PhD, Utah Valley University
Date: 5/14/20
Brief Description: Current research being done at the Utah Women & Leadership Project with specific focus on education, leadership, and women’s well-being
Keywords/Main Subjects: Education, leadership, women’s health
Copyright: copyright Susan Madsen ©2020
Contact: madsensu@uvu.edu

References:

Utah Women’s Health Review Launch

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Title: Launching the Utah Women’s Health Review
Presenter: Karen Schliep, PhD, MSPH; University of Utah, Department of Family and Preventive Medicine
Date: 5/14/20
Brief Description: The public launch of the Utah Women’s Health Review (UWHR)
Keywords/Main Subjects: 7 domains, UWHR, submissions, Eccles Health Sciences Library, CoE, Center of Excellence in Women’s Health
Copyright: copyright Karen Schliep ©2020
Contactkaren.schliep@hsc.utah.edu

Welcome & Introduction

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Title: An Introduction to the Sex, Gender, and Women’s Health Across the Lifespan Symposium
Presenter: Kathleen Digre, MD, Department of Ophthalmology & Visual Science, University of Utah
Date: 5/14/20
Brief Description: An introduction to the Sex, Gender, and Women’s Health Across the Lifespan Symposium, Center of Excellence in Women’s Health, and the 7 Domains of Health
Keywords/Main Subjects: 7 domains, CoE, clinical research and methods (CRAM), Center of Excellence in Women’s Health
Copyright: copyright Kathleen Digre ©2020
Contactkathleen.digre@hsc.utah.edu

Full Symposium Recording

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Content Warning: stillbirth shown 52:12 – 52:42

Full Agenda and Timestamps
————————————–

Welcome & Introduction – 0:00
—Kathleen Digre, MD, University of Utah
Launching the Utah Women’s Health Review – 6:54
—Karen Schliep, PhD, University of Utah
The Status of Women in Utah: Education, Leadership & Well-Being –13:23
Q&A –39:36
—Susan Madsen, PhD, Utah Valley University
—Introduction by Kathleen Digre, MD, University of Utah
WRHR / BIRCWH Scholars Introduction – 44:24
—Michael Varner, MD, University of Utah
Exploring Genetic Variation in Normal & Diseased Human Placentas – 49:15
—Nathan Blue, MD, University of Utah
Progesterone, Post-partum Women and Preventing Methamphetamine Use: Applying Maternal-Fetal Medicine’s Favorite Medicine to Perinatal Substance Abuse – 57:06
—Marcela Smid, MD, MA, MS, University of Utah
Modeling Protection through Preeclampsia – 1:05:28
—Leah Owen, MD, PhD, University of Utah
The Role of Gender in the Diagnosis and Treatment of Complex Disorders – 1:15:49
—Laura Pace, MD, PhD, University of Utah
New Thinking on Sex, Gender, Transgender and Non-Binary Identities – 1:26:00
Q&A – uwhr.utah.edu/new-thinking-on-sex-gender-transgender-and-non-binary-identities
—Lisa Diamond, PhD, University of Utah
—Introduction by Nicole Mihalopoulos, MD, MPH
Data Blitz Introduction – 1:52:47
—Michael Varner, MD, University of Utah
Sex Differences in Subjective Cognitive Decline: Findings from BRFSS (2015–2018) – 1:54:23
—Karen Schliep, PhD, University of Utah
Increasing Afghan-American Women’s Awareness of Cervical Cancer Prevention – 1:59:15
—Nabilah Safi, BSN, University of Utah
Therapeutics Targeting Brain Bioenergetics may be Effective as Antidepressants in Altitude-related Treatment-Resistant Depression: Sex-based Animal Model Studies – 2:04:09
—Shami Kanekar, PhD, University of Utah
Assessing Residents’ Adolescent Sexual and Reproductive Health Knowledge, Confidence, and Self-Efficacy: A Novel Simulated Patient Workshop – 2:08:36
—Jennifer Kaiser, MD, University of Utah; Alyson Shinn, DO, University of Utah; Ocean Candler, BS, Planned Parenthood Associated of Utah
Witnessing Gender-Based Violence Across Borders – 2:13:04
Q&A – 2:27:58
—Annie Fukushima, PhD, University of Utah
—Introduction by Caren Frost, PhD, MPH, University of Utah
Evidence-Based Clinical Care for Midlife Women: What do Research and Clinical Guidelines Tell us? – 2:34:46
—Marjorie Jenkins, MD, MEdHP, FACP, University of South Carolina
—Introduction by Kathleen Digre, MD, University of Utah
Closing Remarks – 3:24:05
—Michael Varner, MD, University of Utah