The Utah Children’s Project: Design, Enrollment and Measures for a Child and Family Cohort

Abstract Objectives: We describe the eligibility criteria, recruitment, and enrollment of the children and families in the Utah Children’s Project. We describe the measurement components of the UCP, including questionnaire instruments, geographically based exposure assessment, direct environmental assessment (including home air quality), DNA extraction, RNA banking, microbiome biosamples, and blood and urine banking. Methods: In …

Endometriosis and hypertriglyceridemia, why we care about severity and typology?

Abstract Background: While plausible mechanisms exist for an association between endometriosis and hypertriglyceridemia, prior studies have shown inconsistent findings, possibly due to the inability to assess endometriosis severity or subtypes. Objectives: Among 473 premenopausal individuals undergoing gynecologic laparoscopy, the present study assessed the association between incident endometriosis and non-fasting serum triglycerides. Methods: Participants were recruited …

Characteristics Associated with Miscarriages in Utah Nail Technicians

Abstract Objective: Previous studies suggest possible worker over-exposure to hazardous chemicals in nail salons. The purpose of this study was to identify exposure characteristics among nail technicians that might be associated with adverse reproductive health outcomes. Methods: Using a cross-sectional design, 937 nail technicians licensed in Utah were invited to complete an online questionnaire regarding …

The association between preconception polycystic ovary syndrome and gestational diabetes mellitus among women with and without pre-pregnancy hypertension: a cross-sectional study from Utah’s Pregnancy Risk Assessment Monitoring System Survey (2016-2021)

Abstract Objectives: The objective of this study is to test the association between preconception polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM) using Utah’s Pregnancy Risk Assessment Monitoring System (2016-2021). In addition, pre-pregnancy hypertension will be tested as a potential effect moderator. Methods: This cross-sectional study utilizes data from Phase 8 of the Utah …

What Role Does Hispanic/Latina Ethnicity Play in the Relationship Between Maternal Mental Health and Preterm Birth?

Abstract Objective: To investigate the association of prepregnancy and prenatal depression and/or anxiety on preterm birth (PTB), while also exploring Hispanic/Latina ethnicity as a potential effect modifier. Methods: Study population included respondents of  UT-PRAMS (2016–2019). Associations between prepregnancy and prenatal depression and/or anxiety and PTB were evaluated using Poisson regression models accounting for stratified survey …

Association Between Pre-pregnancy and Pregnancy Physical Abuse, Partner-related Stress, and Post-partum Depression: Findings from the Utah Pregnancy Risk Assessment and Monitoring System (UT-PRAMS), 2016-2018

Research Synopsis Study question: What is the relationship between pre-pregnancy and pregnancy physical abuse, stressful life events, and post-partum depression (PPD)? What’s already known: Previous research has shown that physical abuse occurring during pre-pregnancy and prenatal is associated with PPD, but limited research has investigated the interplay between physical abuse, life stress, and PPD. What …

Exploring the Dimensions of Adolescent Pregnancy Intendedness, Wantedness, and Planning

Synopsis Study question: How do pregnant adolescent women perceive and understand the pregnancy classification terms “planned,” “wanted,” and “unintended” used by the National Survey of Family Growth?What is already known: The clinical relevance of measuring intended and unintended pregnancy in the National Survey of Family Growth (NSFG) is unclear, particularly to the adolescent population. While …

Fertility Treatment in Utah: A Pooled Analysis of 2009–2015 Utah Pregnancy Risk Assessment Monitoring System (PRAMS) Data

Background Infertility is a common chronic condition affecting 8% to 12% of couples in the United States and worldwide.1-3 Infertility is unique because it is usually experienced by a couple and not an individual. Since the underlying causes of infertility are most commonly (in approximately 50% of cases) due to a combination of male and …

The Baby-Friendly Hospital Initiative (BFHI): An Early Cross-Sectional Analysis of PRAMS Phase 8 Data on Hospital Practices and Breastfeeding Outcomes in Utah and Wyoming

Abstract Introduction: Breastfeeding has immediate and long-term benefits for both maternal and child health.  This study examines the association between Baby-Friendly Hospital Initiative (BFHI) experiences and breastfeeding outcomes in the Mountain West region. Methods: A cross-sectional (retrospective secondary data analysis) was performed using the 2016 Pregnancy Risk Assessment Monitoring System (PRAMS) data. The participants were …

The Association Between Preconception Body Mass Index and Subfertility Among Hispanic and non-Hispanic Women: A Cross-Sectional Study from Utah’s Pregnancy Risk Assessment Monitoring System Survey (2012–2015)

Abstract Objective: To investigate the association between pre-pregnancy body mass index (BMI) and subfertility within a population-based cohort, exploring Hispanic ethnicity as a potential effect modifier. Methods: We used cross-sectional study data from the Utah Pregnancy Risk Assessment Monitoring System from 2012–2015. Relationships between maternal pre-pregnancy BMI and subfertility were evaluated via Poisson regression models …